Interventions for pregnant women living with HIV

PURE Malawi

09/2012 - 08/2016

Funded by the Canadian International Development Agency (CIDA); Mechanism: INSPIRE

Co-Investigator

The PMTCT Uptake and Retention study (PURE Malawi) was a cluster randomized controlled trial that compared two models of peer support to the standard of care. I contributed to a systematic review examining interventions to improve the continuum of care for pregnant women living with HIV in sub-Saharan Africa.

    1. Rosenberg NE, van Lettow M, Tweya H, Kapito-Tembo A, Bourdon CM, Cataldo F, Chiwaula L, Sampathkumar V, Trapence C, Kayoyo V, Kasende F, Kaunda B, Speight C, Schouten E, Eliya M, Hosseinipour M, Phiri S; PURE Malawi Consortium. Improving PMTCT uptake and retention services through novel approaches in peer-based family-supported care in the clinic and community: a 3-arm cluster randomized trial (PURE Malawi). J Acquir Immune Defic Syndr. 2014 Nov 1;67 Suppl 2(0 2):S114-9. doi: 10.1097/QAI.0000000000000319. PMID: 25310116; PMCID: PMC4197136. [Full Text]

    2. Puchalski Ritchie LM, van Lettow M, Pham B, Straus SE, Hosseinipour MC, Rosenberg NE, Phiri S, Landes M, Cataldo F; the PURE consortium. What interventions are effective in improving uptake and retention of HIV-positive pregnant and breastfeeding women and their infants in prevention of mother to child transmission care programmes in low-income and middle-income countries? A systematic review and meta-analysis. BMJ Open. 2019 Jul 29;9(7):e024907. doi: 10.1136/bmjopen-2018-024907. Erratum in: BMJ Open. 2019 Aug 18;9(8):e024907corr1. doi: 10.1136/bmjopen-2018-024907corr1. PMID: 31362959; PMCID: PMC6677958. [Full Text]

    3. Phiri S, Tweya H, van Lettow M, Rosenberg NE, Trapence C, Kapito-Tembo A, Kaunda-Khangamwa B, Kasende F, Kayoyo V, Cataldo F, Stanley C, Gugsa S, Sampathkumar V, Schouten E, Chiwaula L, Eliya M, Chimbwandira F, Hosseinipour MC; PURE Malawi Consortium. Impact of Facility- and Community-Based Peer Support Models on Maternal Uptake and Retention in Malawi's Option B+ HIV Prevention of Mother-to-Child Transmission Program: A 3-Arm Cluster Randomized Controlled Trial (PURE Malawi). J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2:S140-S148. doi: 10.1097/QAI.0000000000001357. PMID: 28498183. [PubMed]

    4. Hosseinipour M, Nelson JAE, Trapence C, Rutstein SE, Kasende F, Kayoyo V, Kaunda-Khangamwa B, Compliment K, Stanley C, Cataldo F, van Lettow M, Rosenberg NE, Tweya H, Gugsa S, Sampathkumar V, Schouten E, Eliya M, Chimbwandira F, Chiwaula L, Kapito-Tembo A, Phiri S; PURE Malawi Consortium. Viral Suppression and HIV Drug Resistance at 6 Months Among Women in Malawi's Option B+ Program: Results From the PURE Malawi Study. J Acquir Immune Defic Syndr. 2017 Jun 1;75 Suppl 2(Suppl 2):S149-S155. doi: 10.1097/QAI.0000000000001368. PMID: 28498184; PMCID: PMC5431274. [Full Text]

    5. van Lettow M, Tweya H, Rosenberg NE, Trapence C, Kayoyo V, Kasende F, Kaunda B, Hosseinipour MC, Eliya M, Cataldo F, Gugsa S, Phiri S; PURE Malawi consortium. Baseline characteristics of study sites and women enrolled in a three-arm cluster randomized controlled trial: PMTCT uptake and retention (pure) Malawi. Reprod Health. 2017 Jul 11;14(1):82. doi: 10.1186/s12978-017-0343-0. PMID: 28693525; PMCID: PMC5504621. [Full Text]

    6. Cataldo F, Chiwaula L, Nkhata M, van Lettow M, Kasende F, Rosenberg NE, Tweya H, Sampathkumar V, Hosseinipour M, Schouten E, Kapito-Tembo A, Eliya M, Chimbwandira F, Phiri S; PURE Malawi Consortium. Exploring the Experiences of Women and Health Care Workers in the Context of PMTCT Option B Plus in Malawi. J Acquir Immune Defic Syndr. 2017 Apr 15;74(5):517-522. doi: 10.1097/QAI.0000000000001273. PMID: 28045712; PMCID: PMC5340586. [Full Text]

    7. Chiwaula LS, Chirwa GC, Cataldo F, Kapito-Tembo A, Hosseinipour MC, van Lettow M, Tweya H, Kayoyo V, Khangamwa-Kaunda B, Kasende F, Trapence C, Gugsa S, Rosenberg NE, Eliya M, Phiri S; PURE Malawi Consortium. The value of informal care in the context of option B+ in Malawi: a contingent valuation approach. BMC Health Serv Res. 2016 Apr 19;16:136. doi: 10.1186/s12913-016-1381-y. Erratum in: BMC Health Serv Res. 2017 Mar 10;17(1):191. doi: 10.1186/s12913-017-2130-6. PMID: 27095249; PMCID: PMC4837588. [Full Text]

    8. Puchalski Ritchie LM, van Lettow M, Hosseinipour MC, Rosenberg NE, Phiri S, Landes M, Cataldo F, Straus SE; PURE consortium. The effectiveness of interventions to improve uptake and retention of HIV-infected pregnant and breastfeeding women and their infants in prevention of mother-to-child transmission care programs in low- and middle-income countries: protocol for a systematic review and meta-analysis. Syst Rev. 2015 Nov 3;4:144. doi: 10.1186/s13643-015-0136-x. PMID: 26525141; PMCID: PMC4630855. [Full Text]

Women’s Health

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    1. Tang JH, Kopp DM, Stuart GS, O'Shea M, Stanley CC, Hosseinipour MC, Miller WC, Mwale M, Kaliti S, Bonongwe P, Rosenberg NE. Association between contraceptive implant knowledge and intent with implant uptake among postpartum Malawian women: a prospective cohort study. Contracept Reprod Med. 2016 Aug 10;1:13. doi: 10.1186/s40834-016-0026-1. PMID: 29201402; PMCID: PMC5693581. [Full Text]

    2. O'Shea MS, Rosenberg NE, Tang JH, Mukuzunga C, Kaliti S, Mwale M, Hosseinipour MC. Reproductive intentions and family planning practices of pregnant HIV-infected Malawian women on antiretroviral therapy. AIDS Care. 2016 Aug;28(8):1027-34. doi: 10.1080/09540121.2016.1140891. Epub 2016 Feb 10. PMID: 26877194; PMCID: PMC4960313. [Full Text]

    3. Sih AM, Kopp DM, Tang JH, Rosenberg NE, Chipungu E, Harfouche M, Moyo M, Mwale M, Wilkinson JP. Association between parity and fistula location in women with obstetric fistula: a multivariate regression analysis. BJOG. 2016 Apr;123(5):831-6. doi: 10.1111/1471-0528.13901. Epub 2016 Feb 8. PMID: 26853525; PMCID: PMC4860061. [Full Text]

    4. O'Shea MS, Rosenberg NE, Hosseinipour MC, Stuart GS, Miller WC, Kaliti SM, Mwale M, Bonongwe PP, Tang JH. Effect of HIV status on fertility desire and knowledge of long-acting reversible contraception of postpartum Malawian women. AIDS Care. 2015;27(4):489-98. doi: 10.1080/09540121.2014.972323. Epub 2014 Nov 4. PMID: 25367269; PMCID: PMC4312510. [Full Text]

    5. Wang J, Hatcher AM, Rosenberg NE. Violence to resilience: structural change to protect adolescent girls. Lancet Child Adolesc Health. 2024 Sep;8(9):613-614. doi: 10.1016/S2352-4642(24)00177-9. Epub 2024 Jul 29. PMID: 39089296. [PubMed]

    6. Pettifor A, Rosenberg N, Behets F. The need to focus on sex workers in generalized HIV epidemic settings. Sex Transm Dis. 2011 Apr;38(4):324-5. PMID: 23330153; PMCID: PMC4487876. [Full Text]

PHASES

01/2017 - 07/2017

Funded by NIH

Co-Investigator

The PHASES Project: Pregnancy and HIV/AIDS Seeking Equitable Study
This project characterizes reasoning around participation in HIV research during pregnancy from the viewpoints of women to inform development of consensus-driven guidance for conducting HIV research in pregnancy. 

    1. Sullivan K, Mtande T, Jaffe E, Rosenberg N, Zimba C, Hoffman I, Little M, Faden R, Lyerly AD. Views among Malawian women about joining HIV prevention clinical trials when pregnant. AIDS Res Ther. 2020 May 27;17(1):27. doi: 10.1186/s12981-020-00271-6. PMID: 32460804; PMCID: PMC7251879. [Full Text]

    2. Sullivan KA, Little MO, Rosenberg NE, Zimba C, Jaffe E, Gilbert S, Coleman JS, Hoffman I, Mtande T, Anderson J, Gross MS, Rahangdale L, Faden R, Lyerly AD. Women's views about contraception requirements for biomedical research participation. PLoS One. 2019 May 8;14(5):e0216332. doi: 10.1371/journal.pone.0216332. Erratum in: PLoS One. 2019 Jun 12;14(6):e0218424. doi: 10.1371/journal.pone.0218424. PMID: 31067273; PMCID: PMC6505940. [Full Text]

    3. Sullivan KA, Little M, Rosenberg NE, Mtande T, Zimba C, Jaffe E, Anderson J, Coleman JS, Gilbert S, Gross Wolf MS, Hoffman I, Rahangdale L, Faden R, Lyerly AD. Women's Views About a Paternal Consent Requirement for Biomedical Research in Pregnancy. J Empir Res Hum Res Ethics. 2018 Oct;13(4):349-362. doi: 10.1177/1556264618783834. Epub 2018 Jul 12. PMID: 29998787; PMCID: PMC6360530. [Full Text]

Adolescent HIV, Sexual, and Reproductive Health

Machine Learning Methods for Assessing Risk

HIV Testing

Interventions for Pregnant Women Living with HIV

Partner, Couple, and Social Network-Based Approaches